BioIntegral Surgical manufactures cardiac and vascular implants made from all-biological materials, using the No-React® treatment. No-React® is a proprietary detoxification of glutaraldehyde-treated tissue.

Grafts are made from bovine pericardium, treated with glutaraldehyde and detoxified with No-React® treatment, stored in 2% saline solution of benzyl-alcohol and do not require rinsing before implantation. No-React® treatment enhances fast endothelialisation within 4-5 weeks after the implantation, thus making the graft resists infection by native endothelial coverage. Bovine pericardium is sutured with continuous sutures with 1 interrupted suture each 2 mm to allow adjusting of the length without un-zipping.

All-biological peripheral vascular graft

• Resist stenosis, calcification, dilatation and thrombosis

• Demonstrated to resist infection

• Made out of bovine pericardium for aorto-iliac or aorto-femoral bypass

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BioIntegral Grafts

BioIntegral Aortic Grafts

No-React® is a proprietary detoxification of a glutaraldehyde-treated tissue. The clinical implications for a prosthesis and patient are significant.

• Reduced toxicity, enhanced biocompatibility

• Lower rates of infections, adhesions and calcifications

• The promotion of endothelial lining