Aziyo Biologics

The CanGaroo Envelope is made up of a naturally occurring bioscaffold that is intended to securely hold both cardiac implantable electronic devices (CIEDs) such as pacemakers and defibrillators and neurostimulators including vagus nerve, deep brain and sacral nerve stimulators as well as spinal cord neuromodulators when implanted in the body. This creates a stabilized environment that may enhance patient comfort and reduce device migration. ¹

CanGaroo® conforms to implantable devices, creating a stabilized environment that may enhance patient comfort.

CanGaroo conforms to the implantable device and remodels into a healthy, vascularized pocket that supports the device, while reducing migration. ¹ Its soft, supple edges may enhance patient comfort, facilitate implantation, and may simplify device removal for exchanges or revisions. ¹ CanGaroo is designed to address the needs of physicians implanting CIEDs and neurostimulators in their daily practice.


• Remodels into systemically connected neovascularized tissue ¹

• Stabilizes implantable devices to reduce risk of device migration and erosion ¹

• Supports and reinforces the pocket

• May ease implantable device removal from pocket during exchange or revision ¹

• Vascularized tissue pocket may enhance patient comfort ¹

• Soft, supple pocket has no sharp edges and conforms to the implantable device to facilitate insertion and may help increase patient comfort

• ECM resists calcification ² ³ ⁴ ⁵


¹ Animal model using CIEDs.

² Sundermann S et al. Thorac Cardiovasc Surg. 2014 Feb;62(1):76-9.

³ Fallon A et al. J Surg Res. 2012 Jun 1;175(1):e25-34.

⁴ Gerdisch M et al. J Thorac Cardiovasc Surg. 2014 Oct;148(4):1370-8.

⁵ Padalino M et al. Interact Cardiovasc Thorac Surg. 2015 Jul;21(1):40-9; discussion 49.

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